Titre

Comparison of 3 Tests for Plasma HIV-1 RNA Quantitation of Non-B Subtypes in Patients Infected with HIV-1 in N’Djamena-Chad: Cobas AmpliPrep/Cobas TaqMan HIV-1 Test Version 2.0, Abbott m2000 RealTime and Generic HIV Viral Load® Assays

Type

Livre

Axe

-,

Secteur

Santé,

Thématique

Epidémiologie,

Recherche

Science Fondamentale (Biologie et Pathogénèses),

Lieu

National,

Source

Chercheurs / Universités,

Auteur

Chatté Adawaye1*, Erick Ntambwe Kamangu2, Joseph Fokam3,4, Fabrice Susin5, Ali Mahamat Moussa6,7, Tchombou Hig-Zounet Bertin6,7, Joseph Mad- Toingué6,7, Dolores Vaira5 and Michel Moutschen5,8

Nombbre de page

6

Année d'édition

2018

Description

Introduction: Antiretroviral therapy is effective only when it maintains the plasma viral load at an undetectable level or below 50 copies of RNA/ml. Viral Load (VL) is a marker of therapeutic follow-up, particularly within the combination protocols of antivirals. Given the genetic diversity of HIV-1, in Resource-Limited Countries (RLCs), dubious conditions for collecting, conserving and analyzing samples, the choice of one technique over another implies its evaluation on all levels and in particular the cost/benefit ratio.

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